Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Polyphosphate Esters as a Synthetic Agent. III. Amide and Peptide Syntheses
金岡 祐一町田 実米光 宰伴 義雄
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1965 年 13 巻 9 号 p. 1065-1072

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PPE(polyphosphate esters) was shown to be a good agent for amide synthesis from a variety of carboxylic acids and primary amines. It also effected imide cyclization. Though in the presence of PPE peptide derivatives were obtained by coupling aminoacids or peptides, full racemization took place. The structure of PPE was discussed with brief review of literatures.
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© The Pharmaceutical Society of Japan
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