Studies on Food Additives. XIII. Synthesis of Arylurea N-Glucuronide from Glucuronolactone

Abstract

1-[3-(Aryl) ureido]-1-deoxy-D-glucofuranuronolactones were synthesized from arylureas and glucuronolactone. Some of them were converted to ammonium 1-[3-(aryl)-ureido]-1-deoxy-β-D-glucopyranuronates by treatment with alkaline, which were identical with metabolites from the rabbit urine dosed with the corresponding arylureas.