Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Benzochromones. IX. Syntheses of Hydroxyl Derivatives of 2-Methyl-5, 6-benzochromone and 2-Methyl-3-acetyl-5, 6-benzochromone
Akira UenoSeigo Fukushima
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1966 Volume 14 Issue 2 Pages 129-139

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Abstract
Syntheses of hydroxyl derivatives of 2-methyl-5, 6-bezochromone were investigated, and following benzochromone derivatives were obtained together with related compounds, and physical and chemical properties of these chromones were characterized : 2-Methyl-8-methoxy-5, 6-benzochromone (IV), 2-methyl-7-methoxy-5, 6-benzochromone (X), 2-methyl-7, 8-dimethoxy-5, 6-benzochromone (XIV), 2-methyl-3-acetyl-8-methoxy-5, 6-benzochromone (XXV), 2-methyl-3-acetyl-7-methoxy-5, 6-benzochromone (XXII), and 2-methyl-3-acetyl-7, 8-dimethoxy-5, 6-benzochromone (XXIII). Hydroxylation of 2-methyl-8-hydroxy-5, 6-benzochromone (III) or 2-methyl-7-hydroxy-5, 6-benzochromone (V) gave 2-methyl-7, 8-dihydroxy-5, 6-benzochromone (XX) from both.
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© The Pharmaceutical Society of Japan
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