Studies on the Morphine Alkaloids and Its Related Compounds. XIV. Preparation of 6-Amino-hydrophenanthrene Compounds from Hofmann Degradation Products of the Morphine Alkaloids.
1966 年 14 巻 5 号 p. 453-461
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1966 年 14 巻 5 号 p. 453-461
Preparation of 6-amino-hydrophenanthrene compounds from the 6-oxo-hydrophenanthrene compounds derived by the Hofmann degradation reaction of the 6-oxo-morphine alkaloids was described. There have been used catalytic reductive amination of the 6-oxo-compounds and catalytic, sodium borohydride, and formic acid reductions of their enamine derivatives. Behaviors of the 6-oxo-compounds in the described reactions were quite similar to those of the 6-oxo-morphines reported previously.
