Studies on Pore Structure of Granules by Mercury Porosimetry

Abstract

1. The pore-size distribution and the pore structure of sucrose and lactose granules were determined by mercury porosimetry. The detailed informations on the pore structure could be obtained by scanning curves, and the property of pore structure could be estimated by the difference curve roughly. 2. The granules prepared by a wet granulation method have the greater pore-size when less amount of water is added, and vice versa. 3. The granules prepared with powder of greater particle-sizes have the greater pore-sizes.