抄録
Three new N-[2-(3-indolyl)ethy1] thioamides (IIa∼c) and N-(methylthiocarbony1) tryptophan methyl ester (III) were conveniently prepared according to our general procedure of synthesizing thioamides. The cyclodesulfurization of IIa∼c was successfully accomplished in high yield to the corresponding 1-subsituted-3, 4-dihydro-9H-pyrido[3, 4-b]-indole derivatives (IVa∼c). In addition, III was cyclized to give a mixture of both 1-methy1-3, 4-dihydro-9H-pyrido[3, 4-b]indole-3-caroxylic acid (Vb), and its methyl ester (Va) in excellent yield.
