Abstract
Treatment of 3α, 5α-cyclo-6, 19-dioxosteroid (II) in a boiling mixture of diluted sulfuric and acetic acids afforded 1β, 4β-oxido-6-oxo-Δ5 (10)-A-homo-19-norsteroid (III), together with a small amount of 3β-acetoxy-6, 19-dioxosteroid (IV), the latter compound, under the same reaction conditions, being converted to the former. The structure of the rearrangement product (III) was discussed. A-homo-19-nortestosterone (XXV) was synthesized from 1β, 4β-oxido-17β-hydroxy-A-homo-19-norandrost-5 (10)-en-6-one acetate (III : R=[chemical formula]).
