Abstract
Alkaline degradation of azalomycin-B, a macrolide antibiotic produced by Streptomyces hygroscopicus var. azalomyceticus, afforded oct-4-en-3-one (II), an unsaturated keto-alcohol (X), and 2, 4-dimethylphenylacetic acid (VIII), accompanied with lower-graded degradation products. Based on elucidated structures of these products, a partial structure of (XIV) was proposed for this antibtotic.
