Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
A Fluorometric Method for the Estimation of Benhepazone.
村田 寿和田 忠男
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1967 年 15 巻 12 号 p. 1906-1909

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Benhepazone is activated maximally at 395 mμ and emits a fluorescence which shows a maximum at 410 mμ. Furthermore, Benhepazone was found to be quantitatively extracted into chloroform in alkaline conditions from a mixture consisting of Benhepazone and related compounds. On the basis of these findings, a fluorometric method has been adopted for the measurement of Benhepazone in tissues, urine, and feces. A procedure for assaying Benhepazone consists of its extraction with chloroform followed by the measurement of its fluorescence intensity at 410 mμ and it has been ascertained that neither metabolic products of Benbepazone nor native substances in biological samples interfered by the determination of Benhepazone in the course of this procedure.

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© The Pharmaceutical Society of Japan
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