Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Pyrimidine Derivatives and Related Compounds. XLVII. Reaction of Thiamine with Dialkyl Acylphos-phonates or Methyl Phenylacyl-phosphinates : Takamizawa Reaction 6
高見沢 映佐藤 義朗佐藤 久夫
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1967 年 15 巻 8 号 p. 1183-1187

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Several kinds of dialkyl acylphosphonate (IIIa∼d, Va∼d) were synthesized and reacted with thiamine to give 1, 6-dihydropyrimido [4', 5'-4, 5] pyrimido [2, 3-c] [1, 4] thiazine derevatives (XIIA, B, XIIIA, B). Methyl phenylacylphosphinate also gave same result.

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© The Pharmaceutical Society of Japan
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