Studies on the Alkaloids of Menispermaceous Plants. CCXLIII. Syntheses of Dauricine Type Bases. (3). Synthesis of dl-Cuspidaline and dl-4'-O-Methylberbamunine

Abstract

A synthesis of dl-cuspidaline and dl-4'-O-methylberbamunine was carried out through Bischler-Napieralski reaction followed by separation of the diastereoisomers. The configuration of each racemic diastereoisomer was ascertained by NMR comparisons with the bases of known absolute configuration.