Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Synthesis of Bradykinyl-peptide and Peptidyl-bradykinin
鈴木 謙次安孫子 敬
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ジャーナル フリー

1968 年 16 巻 10 号 p. 1997-2004

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[6-O-Acetyl-L-serine]-bradykinyl-glycyl-L-valyl-L-glutamine, glycylglycyl-L-lysylbradykinin, and bradykinylglycine were synthesized for the elucidation of structure activity relationship of bradykinin and their properties as substrates for bradykininreleasing enzymes. The p-nitrophenyl ester method and stepwise elongation procedure were extensively used for the peptide synthesis.
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© The Pharmaceutical Society of Japan
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