Chemical Studies on Chlorine-containing Peptide-One of the Toxic Metabolites of P. islandicum Sopp. I. Structure and Synthesis of Dehydrochlorinated-Peptide Amide

抄録

An attempt was made to synthesize dehydrochlorinated-peptide amide (II), which is obtained by treating the chlorine-containing peptide (I) isolated from Penicillium islandicum Sopp. with concentrated ammonia water. It was concluded from the results of the present investigation that the structure of dehydrochlorinated-peptide amide (II) should be presented as α-pyrrolecarboxylyl-L-α-amino-n-butyryl-L-seryl-L-β-amino-β-phenylpropionyl-L-serine amide (XIX).