Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
The Synthesis of 2, 3-Dimethoxy-5-methyl-p-benzoquinone and Related Compounds
越 克己清水 正夫
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1968 年 16 巻 12 号 p. 2343-2350

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2, 3-Dimethoxy-5-methyl-p-benzoquinone (IV), a synthetic intermediate of ubiquinones was prepared in excellent yield by oxidation of 2, 3-dimethoxy-5-methyl-p-phenylenediamine dihydrochloride (XIV) obtained via 3, 4-dimethoxy-2, 5-dinitrobenzaldehyde (XII) from vanillin. A number of p-benzoquinones related to IV were also synthesized for biological evaluation.
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© The Pharmaceutical Society of Japan
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