Studies on the Metabolic Products of Aspergillus fumigatus (J-4). Chemical Structure of Metabolic Products

Abstract

Several new pigments produced by a fungus A spergillus fumigatus (J-4) were studied. The structures were determined as 2-chloro-1, 3, 8-trihydroxy-6-methylanthrone (9) (I), 2-chloro-1, 3, 8-trihydroxy-6-methylanthraquinone (II), 2-chloro-1, 3, 8-trihydroxy-6-hydroxymethylanthraquinone (III) and emodin. The chlorinated monoanthrone derivative is the first case in natural products. When Cl- was replaced by Br-in the medium, the fungus produced corresponding brominated anthrone (IV).