Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Syntheses of 6-Amino-1-phenylisoquinolines by Bischler-Napieralski Reaction
SABURO ISHIWATAKEIICHI ITAKURA
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1968 Volume 16 Issue 5 Pages 778-783

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Abstract
Ethoxycarbamido group was shown to be a good substituent for accelerating Bischler-Napieralski reaction of β-phenethylbenzamides as well as alkoxy group and ring-closure occurred selectively at the para position to the ethoxycarbamido group. And an improved synthesis of aminoisoquinoline was achieved by Bischler-Napieralski reaction.
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© The Pharmaceutical Society of Japan
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