1968 Volume 16 Issue 5 Pages 799-805
The reaction of 1-substituted biguanide with phenylenedicarboxylic acid ethyl ester afforded 2-amino-4-(substituted amino)-6-carboxyphenyl-s-triazine (II) along with 2, 2'-phenylenebis [4-amino-6-(substituted amino)-s-triazine] (XIII and XVI). Product II was derived to its guanidinium salt. The related reactions concerned to the above synthetic methods, were also described. Moreover, 2-amino-4-(substituted amino)-6-hydroxyalkyl-s-triazine (IV) was synthesized from the condensation of 1-substituted biguanide with lactone compound.