Studies on Metabolism of 3-Desoxyestrone. I. Synthesis of 16, 17-Oxygenated Estra-1, 3, 5 (10)-trienes

Abstract

For the studies on the fate of 3-desoxyestrone in man, estra-1, 3, 5 (10)-trienes having oxygen functions at C-16 and/or C-17, its possible metabolites, have been synthesized as shown in Chart 1.