Studies on the Synthesis of Pyridazine Derivatives. XI. Reaction of 3, 6-Dialkoxypyridazine 1-Oxide with Alkylhalides, Haloketones and Haloacid Esters, and Decomposition of Reaction Products

Abstract

Reaction of 3, 6-dialkoxypyridazine 1-oxides (I) with halogeno compounds afforded corresponding esters of cyclic hydroxamic acid (II). Decomposition of II with acids, alkalines and pyrolysis gave aldehydes and 3-alkoxy-6 (1H) pyridazinones (V), or conjugated carbonyl olefines and 1-hydroxy-3-alkoxy-6 (1H) pyridazinones (IV), respectively.