Studies on the Method of Thermal Analysis of Organic Medicinals. VI. Simultaneous Measurement of the Differential Temperature and of the Dielectric Behavior

Abstract

A new semimicro apparatus for the simultaneous measurement of the differential temperature and the dielectric behavior was constructed and the characteristics of the electric circuits for these physical parameters were discussed. Also, tests concerning dehydration of copper sulfate pentahydrate and glucuronamide monohydrate, polymorphic transition of potassium nitrate and molecular compound formation between aminopyrine and barbital were carried out. The results indicate that the apparatus is sensitive to any one of these phase reactions and is superior to the monofunctional thermal analyzer, especially in that the formation of aqueous solution from a hydrate and the end point of some kinds of phase reactions are more clearly determined.