抄録
In order to examine the relationships between the structure and activity in anabolic steroids, 17α-methyltestosterone and 17α-methyldihydrotestosterone derivatives containing 7α-alkylthio and/or 7α-arylthio groups were synthesized. Some of these compounds possess high myotrophic activity with a favorable myotrophic-androgenic ratio. Preparation of androstano-isoxazoles and isoxazolines having the 7α-ethylthio group was also described.
