抄録
For the selective reduction of carboxyl groups in peptides, diborane and sodium borohydride were examined. Because of accompanying reductive side reaction, the reduction of carboxyl groups with diborane in tetrahydrofuran was unsatisfactory. On the other hand, by the use of sodium borohydride in aqueous solution, certain model peptide esters were easily reduced to corresponding alcohols without any appreciable side reaction.
