Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Catalytic Hydrogenation of Hydroamide in the Presence of Ammonia and of Butylamine
KEIICHI ITOMINORU SEKIYA
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1969 Volume 17 Issue 5 Pages 861-865

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Abstract
Catalytic hydrogenations of hydroamides under high hydrogen pressure in the presence of ammonia and of butylamine were examined to see effects of these bases on the composition of products. The product analyses show the predominant formation of primary amine in the former case and in the latter case the formation of primary and secondary amines possessing butyl residue at 2 : 1 molar ratio. From these results comments on the course of the hydrogenation are given.
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© The Pharmaceutical Society of Japan
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