In order to test of antimicrobial activity, 1-ethyl-1, 4-dihydro-7-[2-(5-nitro-2-furyl)-vinyl]-4-oxo-1, 8-naphthyridine-3-carboxylic acid (V) which contained nalidixic acid and 5-nitro-2-furaldehyde was prepared and a convenient method for the synthesis of its derivatives was studied.
