Abstract
An investigation was made of the effect of ionic head of cationic surface active agents on their hemolytic activity. When the number of carbon atoms in the alkyl radical is less than 8, there appeared to exist a close relation between the adsorbability and the hemolytic activity (amount adsorbed per cell necessary to cause hemolysis) of the cationic agents. However, no direct correlation could be found if the number of carbon atoms exceeds 8. This was interpreted as implying that too high the adsorbability of surface active cations with a long hydrophobic tail and a large ionic head may adversely affect the hemolytic activity of these ions.
