抄録
The NOE's of the pyrrolidine ring protons, HA and HB, on the phenyl ring protons of the N-substituent, HD, were determined in 1-(p-methoxyphenyl)-3, 4-epiminopyrrolidine (2), its N-benzyl derivative (1), and its N-acetate (12). Notable differences of NOE's observed in the latter two compounds suggested that the p-methoxyphenyl group is preferentially situated on the same side as the cis-fused aziridine ring in these compounds. Synthesis of some 3, 4-epiminopyrrolidines was also reported in connection with this NOE study.
