Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Structure of a Product of a Fluorescence Reaction of 3-Hydroxykynurenine
渡邊 光夫田村 善藏岡田 正志
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1970 年 18 巻 2 号 p. 285-290

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A product of fluorescence reaction of 3-hydroxykynurenine with p-toluenesulfonylchloride was separated and its structure was investigated. A reaction product of 2-amino-3-hydroxyacetophenone, which has the same configuration of carbonyl, amino and hydroxyl groups, with p-toluenesulfonylchloride was also studied. It was shown that the product from 3-hydroxykynurenine was p-toluenesulfonylester of the 3-hydroxyl group and p-toluenesulfonylamide of the aliphatic amino group, and that the product from 2-amino-3-hydroxyacetophenone was p-toluenesulfonylester of the 3-hydroxyl group.
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© The Pharmaceutical Society of Japan
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