Abstract
Alkyl and glycosyl migration reactions of N-1, N-3, N-7 and N-9 substituted derivatives of adenine, N6, N6-dimethyladenine, N2-acetylguanine and purine were demonstrated. In addition, the chemical shifts of these derivatives in nuclear magnetic resonance (NMR) were determined and the frontier π-electron densities of nitrogens in purine ring were calculated by simple LCAOMO method. These results provided the order of thermodynamical stability and kinetical favour of the derivatives on the alkylation reaction.
