Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Chemistry of Diborane and Sodium Borohydride. VII. Reduction of α-Amino Acid Amides with Sodium Borohydride
ISAO SAITOYASUO KIKUGAWASHUNICHI YAMADA
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1970 Volume 18 Issue 9 Pages 1731-1736

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Abstract
Tertiary amides of five amino acids and their derivatives were reduced with sodium borohydride in refluxing pyridine to the corresponding diamines in moderate yields. Effects of substituents at the α-position on α-substituted N, N-dimethylhydrocinnamamide were examined.
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© The Pharmaceutical Society of Japan
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