Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Relationship between Carcinogenicity and Electronic Structure of Mononitroquinolines
栗原 照夫市村 弘子井垣 哲夫太田 明廣
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1971 年 19 巻 1 号 p. 37-40

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It was found that a certain relation seems to exist between the carcinogenic action of mononitroquinoline and the approximate superdelocalizabilities of the carbon atom to which the nitro group is attached. Referring to these results, the approximate superdelocalizabilities of some derivatives of 2- and 4-nitroquinolines were also calculated, and a relationship between the chemical structure and the carcinogenicity was discussed.
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© The Pharmaceutical Society of Japan
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