Abstract
The injection of β-mercaptoethylguanidine bromide hydrobromide (MEG) together with cysteamine hydrochloride (MEA) afforded better protection of mice against Xirradiation than the injection of either compound alone, while the two compounds did not act additively in the display of the acute toxicity. The powerful effectiveness of the MEG-MEA mixture was not attributable to the formation of a mixed disulfide, aminoethyl guanidinoethyl disulfide (AEGE) in the solution or in the animal body. The latter compound was synthesized and proved very toxic but weak in the radioprotective activity.
