Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Electrodialytic Extraction in Drug Analysis. II. Examination of Ordinary Drugs from the Extractability View Point
NOBUTAKA TSUNAKAWA
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1971 Volume 19 Issue 12 Pages 2579-2584

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Abstract
In order to evaluate the electrodialytic extraction method, a large number of drugs were extracted with the proposed apparatus, and the following results were obtained. 1. Organic acids, sulfonamides, amino acids and barbiturates could be extracted by using 0.5M NH4OH as a basic carrier solution. 2. Amines, sulfonamides and amino acids could be extracted by using 0.5M acetic acid as an acidic carrier solution. 3. Substances which have very low dissociation constant could be made into useful carrier solution by adding a strong electrolyte such as NaCl. The most desireable specific conductivity is about 1.0×10-3 mho/cm. 4. Some sugars could be extracted in the form of borate complex.
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© The Pharmaceutical Society of Japan
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