Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Structural Studies on Complexes. VI. X-Ray Investigation of A 2 : 1 5-Chlorosalicylic Acid : Theobromine Complex
ELI SHEFTERTHOMAS F. BRENNANPHYLLIS SACKMAN
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1971 年 19 巻 4 号 p. 746-752

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The dominant force of attraction in the 2 : 1 5-chlorosalicylic acid : theobromine crystalline complex is hydrogen bonding. There are three relatively strong hydrogen bonds, all involving a carboxyl group of the salicylate. A substantial degree of π overlap exists between the phenyl ring of the acid and the xanthine nucleus.

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