Studies of Nucleosides and Nucleotides. XLIII, Purine Cyclonucleosides.(10). Optical Rotatory Dispersion and Circular Dichroism of Adenine 8-Cyclonucleosides

Abstract

Optical rotatory dispersion and circular dichroism of 8-cyclonucleosides derived from adenosine were measured.
In the β-cyclonucleosides magnitude of rotatory strengths increased in the order 8, 2'-<8, 3'-<8, 5'-cyclonucleoside both in the case of O- and S-cyclonucleosides. All of these cyclonucleosides had positive Cotton curve at absorption maxima.
In α-cyclonucleoside the sign of the Cotton effect inverted to negative and the magnitude is almost same with β-cyclonucleoside.