Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on the Gastrointestinal Hormones. V. Distribution of Gastric Secretory Inhibiting Substance in Whale Gastrointestinal Mucosa
HISATOSHI KABENOTETURO HONDAYASUAKI KOBAYASHITOSHIRO MURATA
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1971 Volume 19 Issue 7 Pages 1487-1490

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Abstract
Gastrone, enterogastrone, and secretin have been known as the substances contained in mammalian digestive tract and having inhibitory action on the secretion of gastric juice.
A glycoprotein fraction, designated as E fraction, has been isolated from the gastric mucosal layer of finback whale and found to have a marked inhibitory action on the gastric juice secretion by the authors.
In order to clarify the mechanism of the inhibitory action on the gastric juice secretion, the distribution of the substance in the mucosal layer of gastrointestinal tissues from the 3rd stomach to small intestine of sperm whale was studied in this paper.
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© The Pharmaceutical Society of Japan
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