Studies on Ketene and Its Derivatives. XLVI. Mass Spectrometric Studies of 3-Acetyl-4-hydroxy-6-methyl-l-pyridyl-2-pyridones and N-Pyridy1-2, 6-dimethy1-4-pyrone-3-carboxamides

Abstract

The reaction of diketene with amino-methylpyridines (Ia-i) was investigated, and the products were identified by the mass spectroscopic study. The reaction of 2-(Ia) and 3-amino-methylpyridines (Ib, d, f, h) with diketene gave the pyridone derivatives (IIIa, b, d, f, h), but 4-amino-methylpyridines (Ic, e, g, i) afforded the pyrone derivatives (IVc, e, g, i). The mass spectrum of III showed the characteristic peaks at m/e 243, 215, 187 and 175, and in the case of IV the strong peaks were observed at m/e 151, 108, 67 and 43. Each fragmentation pathways were discussed.