Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Formic Acid Reduction. XIV. Formation of 3-Arylphthalimidines from 3-Aryl-3-hydroxyphthalimidines
MINORU SEKIYAYOSHIYASU TERAO
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1972 Volume 20 Issue 10 Pages 2128-2133

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Abstract
It has now been found that reduction of 3-aryl-3-hydroxyphthalimidines to 3-arylphthalimidines are easily effected on heating with the formate reagent, TMAF, known as a constant boiling liquid composed of formic acid and trimethylamine. Fashon of the attack of formic acid in this reaction was clarified by means of using deuterated formate reagent.
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© The Pharmaceutical Society of Japan
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