Constituents of Chinese Crude Drug"Wujiapi."VII. On the Structure of Glycoside E of Bei-Wujiapi

Abstract

The chemical structure of glycoside E (Ia), C₂₇H₄₄O₆, mp 239-240°, [α]²²_D-69.9°, which was isolated from Bei-Wujiapi (cortex of Periploca sepium BGE.), was established to be ⊿⁵-pregnene-3β, 17α, 20α-triol (20)-β-D-canaropyranoside. It is interesting that glycoside E is the second example of the pregnane type glycoside whose sugar moiety links to the C₂₀-hydroxyl group other than C₃-hydroxyl group of the aglycone.