Abstract
Secondary amines such as diethylamine (II), piperidine (IV), and 2-ethylpiperidine (VI) were allowed to react with N, N-dichlorophenylacetamide (I) to give N, N-diethyl-N'-benzylurea (III), benzylcarbamoylpiperidine (V), and benzylcarbamoyl-2-ethylpiperidine (VII), respectively. Three moles of amines were consumed to complete the reactions, that is, urea derivatives, amine hydrochlorides, and N-chloroamines were produced, simultaneously. The latters were reduced with sodium bisulfite to give amine hydrochlorides. The mechanism of these reaction was also discussed.
