Abstract
Bradykinin, a nonapeptide local tissue hormone, was synthesized by the use of the isobornyloxycarbonyl (IBOC-)-protecting group for the temporary protection of the all amino groups of the intermediary peptides. During the synthesis of bradykinin, no complication occurred in the processes involving the introduction and removal of the IBOC-group, and the final synthetic hormone showed up to possess the full biological activity and appeared to be pure by chemical criterions.
