Reaction of Biguanides and Related Compounds. IV. Reaction of Arylbiguanide with Benzoylacetone in the Presence of a Small Amount of the Arylbiguanide Hydrochloride

Abstract

Arylbiguanide reacted with benzoylacetone in the presence of proton to give eightmembered ring compound, 4-amino-2-arylamino-6-methyl-8-phenyl-1, 3, 5-triazacyclooctatetraen. p-Methoxyphenylbiguanide isolated exclusively two isomers, which were easily changed each other by heating. The structure of the compounds were discussed.