Peptide Mode of β-Lysine Residues in Racemomycin-C

Abstract

β-Lysine dipeptide was isolated from the acid hydrolysate of Racemomycin-C and identified with a synthetic sample of ε-N-(L-β-lysyl)-L-β-lysine. Similarly, β-N-dinitro-phenyl-L-β-lysine and β-N, N-dimethyl-L-β-lysine were respectively isolated from the acid hydrolysate of dinitrophenylated Racemomycin-C and hexa-N-methyl Racemomycin-C and identified with authentic samples. These results confirm that β-lysine peptide sequence of Racemomycin-C is ε-peptide bond.