Abstract
Optically active 2-bromocyclohexanone derivatives were asymmetrically synthesized for the first time. Absolute configurations of products were determined using the axial α-haloketone rule. The solvent effect of (-)-V on optical rotatory dispersion and circular dichroism was studied in various solvents.
Racemization of (-)-V catalyzed with acid or base was examined. Asymmetric synthesis using other ketones was also studied.
