Nucleosides. LXXX. Synthetic Studies of Nucleoside Antibiotics. 10. Synthesis of 1-[2, 3, 4-Trideoxy-4-(sarcosyl-D-seryl) amino-β-D-erythrohex-2-enopyranosyluronic acid] cytosine, the Nucleoside of Blasticidin S Bearing the Dipeptide of Gougerotin

K.A. WATANABE; J.J. FOX

doi:10.1248/cpb.21.2213

Nucleosides. LXXX. Synthetic Studies of Nucleoside Antibiotics. 10. Synthesis of 1-[2, 3, 4-Trideoxy-4-(sarcosyl-D-seryl) amino-β-D-erythrohex-2-enopyranosyluronic acid] cytosine, the Nucleoside of Blasticidin S Bearing the Dipeptide of Gougerotin

K.A. WATANABE, J.J. FOX

著者情報

ジャーナルフリー

1973 年 21 巻 10 号 p. 2213-2216

DOI https://doi.org/10.1248/cpb.21.2213

詳細

抄録

A"hybrid"which contains the nucleoside moiety of blasticidin S and the dipeptide group of Gougerotin was synthesized by step-wise linkage of sarcosine and D-serine to cytosinine using the dicyclohexylcarbodeimide (DCC) procedure.

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