Studies on 1-Alkyl-2 (1H)-pyridone Derivatives. XVII. Reaction of 1-Methyl-2 (1H)-thiopyridone with Hydrochloric Acid and Formaldehyde

HIROSHI TOMISAWA; KAZUHIRO KOSAKA; HIROSHI HONGO; REIKO FUJITA; HIDEKI KATO; CHAOHSIUNG WANG

doi:10.1248/cpb.21.2590

富沢宏, 高坂和弘, 本郷弘司, 藤田礼子, 加藤秀樹, 王昭雄

著者情報

ジャーナルフリー

1973 年 21 巻 12 号 p. 2590-2593

DOI https://doi.org/10.1248/cpb.21.2590

詳細

抄録

Reaction of 1-methyl-2 (1H)-thiopyridone with formaldehyde and hydrochloric acid was carried out. The main product in this reaction was 3-hydroxymethyl-1-methyl-2 (1H)-thiopyridone (IV) in 22% yield. The structure of products in this reaction were confirmed by their nuclear magnetic resonance spectral comparison.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）