Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Syntheses of Catechol Estrogen 16, 17-Ketols, New and Potential Metabolites
TOSHIO NAMBARA, YOSHIHIKO KAWARADA, MIKIKO ASAMA, SETSUKO AKIYAMA, MUNETAKA NOKUBO, SEIJIRO HONMA
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1973 Volume 21 Issue 12 Pages 2725-2732

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Abstract
In order to characterize the biliary metabolites the catechol estrogen 16, 17-ketols and their monomethyl ethers have been synthesized as reference compounds employing the method worked out by Gallagher and his co-workers. The preparation of 2-methoxy-16α-hydroxyestrone 3-glucuronide acetate-methyl ester (Vd) has also been described.
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© The Pharmaceutical Society of Japan
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