Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Benzoheterocyclic Derivatives. XIII. Synthesis and Pharmacological Actions of Indoline Derivatives.(4)
NORIYASU HIROSESHIGERU SOHDASHIZUO KURIYAMASHOJI TOYOSHIMA
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1973 Volume 21 Issue 5 Pages 960-971

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Abstract
Thirty one derivatives of 3-alkoxy-1[ω-(N-substituted amino)-3-phenylindolin-2-one and related compounds were synthesized for pharmacological testing. As a preliminary screening test compounds were tested for analgetic-antiphlogistic activity by anti-writhing test in mice. Acute toxicity and gross behavioral changes in mice were also determined. The majority of the compounds produced anti-writhing activity.
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© The Pharmaceutical Society of Japan
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