抄録
In the presence of Cu and 2-(2-hydroxyethyl)pyridine, flufenamic acid formed a chelate compound, which could be extracted with propyl acetate. The amount of flufenamic acid was obtained indirectly by measuring Cu in this propyl acetate solution by atomic absorption. When this method was applied to the perfusion of the rat small intestine and to the analysis of preparations, good results were obtained without any interference. It was also found that flufenamic acid, Cu, and 2-(2-hydroxyethyl)pyridine combined in the ratio of 1 to 1 to 1 to form a chelate.
