Detection of Amphetamine and Related Amines in Urine by Gas Chromatography and Combined Gas Chromatography-Mass Spectrometry

Abstract

A method using gas chromatography and combined gas chromatography-mass spectrometry techniques for the detection of amphetamine and related amines in urine was investigated. The perfluoroacyl derivatives of these amines have excellent gas chromatographic and mass spectrometric properties. Typical fragmentation processes in their mass spectra were also discussed.