Abstract
Reaction of methyl 2-cyano-3-(2-substituted indol-3-yl) thio-3-methylthioacrylates (III) with various nucleophilic reagents (amines, active methylene compounds) resulted in the formation of products by substitution of the methylthio or the indolylthio group. Treatment of these compounds (III, IVa, IVd) with 10% hydrochloric acid gave thieno-[3, 2-b] indole derivatives 3-methoxycarbonyl-2-methylthiotbieno [3, 2-b] indole, 2-benzyl-amino-3-methoxycarbonylthieno [3, 2-b] indole, 3-carbamoyl-2-(methylthio) thieno [3, 2-b]-indole.
